Cathepsin E antibody (AA 157-187)

Catalog No. ABIN390486

The Rabbit Polyclonal anti-Cathepsin E antibody (Clone RB19246) (ABIN390486) specifically detects Cathepsin E in WB, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Cathepsin E antibody (AA 157-187) (ABIN390486)

Target: Cathepsin E (CTSE)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin E antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19246

Product Details anti-Cathepsin E Antibody

Binding Specificity: AA 157-187

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500-1:2000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Cathepsin E

Target: Cathepsin E (CTSE)

Alternative Name: CTSE

Background: CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.

Molecular Weight: 42794

Gene ID: 1510

NCBI Accession: NP_001901, NP_683865

UniProt: P14091