GNPAT antibody

Catalog No. ABIN498958

Product Details anti-GNPAT Antibody

Target: GNPAT (Glyceronephosphate O-Acyltransferase (GNPAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPAT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of GNPAT protein. (region surrounding Phe365)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GNPAT

Target: GNPAT (Glyceronephosphate O-Acyltransferase (GNPAT))

Alternative Name: GNPAT / DAPAT (GNPAT Products)

Synonyms: GNPAT antibody, dhapat antibody, DAP-AT antibody, DAPAT antibody, DHAPAT antibody, AU019525 antibody, D1Ertd819e antibody, glyceronephosphate O-acyltransferase antibody, glyceronephosphate O-acyltransferase S homeolog antibody, GNPAT antibody, gnpat antibody, NAEGRDRAFT_77877 antibody, gnpat.S antibody, Gnpat antibody

Background: GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.Synonyms: Acyl-CoA:dihydroxyacetonephosphateacyltransferase, DHAPAT, Dihydroxyacetone phosphate acyltransferase, Glycerone-phosphate O-acyltransferase

Molecular Weight: approx. 77 kDa

Gene ID: 8443

NCBI Accession: NP_055051

UniProt: O15228

Pathways: Cell-Cell Junction Organization