GNPAT antibody (AA 201-300)

Catalog No. ABIN709106

The Rabbit Polyclonal anti-GNPAT antibody is suitable to detect GNPAT in samples from Human. It has been validated for ELISA, WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for GNPAT antibody (AA 201-300) (ABIN709106)

Target: GNPAT (Glyceronephosphate O-Acyltransferase (GNPAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPAT antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GNPAT Antibody

Binding Specificity: AA 201-300

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNPAT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNPAT

Target: GNPAT (Glyceronephosphate O-Acyltransferase (GNPAT))

Alternative Name: GNPAT

Background:

Synonyms: DAPAT, DAP-AT, DHAPAT, Dihydroxyacetone phosphate acyltransferase, DHAP-AT, Acyl-CoA:dihydroxyacetonephosphateacyltransferase, Glycerone-phosphate O-acyltransferase, GNPAT

Background: GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.

Gene ID: 8443

UniProt: O15228

Pathways: Cell-Cell Junction Organization