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GGH antibody
GGH
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GGH Antibody
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Target
See all GGH Antibodies
GGH
(gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) (GGH))
Reactivity
All reactivities for GGH antibodies
Human
Host
All hosts for GGH antibodies
Rabbit
Clonality
All clonalities for GGH antibodies
Polyclonal
Conjugate
All conjugates for GGH antibodies
This GGH antibody is un-conjugated
Application
All applications for GGH antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of GGH protein. (region surrounding Lys287)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography using epitope-specific immunogen
Purity
> 95 % (by SDS-PAGE)
Top Product
Discover our top product GGH Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for GGH
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Target
GGH
(gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) (GGH))
Alternative Name
gamma-Glutamyl Hydrolase / GGH (GGH Products )
Synonyms
CK2A2 antibody, CSNK2A1 antibody, GH antibody, gamma-GH antibody, zgc:76958 antibody, wu:fa56a05 antibody, wu:fj90a01 antibody, MGC84044 antibody, GGH antibody, MGC130662 antibody, ATGGH2 antibody, gamma-glutamyl hydrolase 2 antibody, casein kinase 2 alpha 2 antibody, gamma-glutamyl hydrolase antibody, gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) antibody, gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) L homeolog antibody, gamma-glutamyl hydrolase 2 antibody, Gamma-glutamyl hydrolase antibody, CSNK2A2 antibody, GGH antibody, Ggh antibody, ggh antibody, ggh.L antibody, ggh.2.L antibody, GGH2 antibody, GH antibody
Background
GGH (gamma-glutamyl hydrolase), also known as GH or Gamma-Glu-X carboxypeptidase, is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome. Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, specifically hydrolyzing gamma-glutamyl bonds. Via its catalytic activity, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates. Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, inflammatory bowel disease and various cancers.Synonyms: Conjugase, GH, Gamma-Glu-X carboxypeptidase
Molecular Weight
approx. 36 kDa
Gene ID
8836
NCBI Accession
NP_003869
UniProt
Q92820
Pathways
SARS-CoV-2 Protein Interactome
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