PTGR1 antibody

Catalog No. ABIN499095

Product Details anti-PTGR1 Antibody

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGR1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of LTB4DH protein. (region surrounding Leu105)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for PTGR1

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Alternative Name: Prostaglandin Reductase 1 (PTGR1 Products)

Synonyms: LTB4DH antibody, PGR1 antibody, ZADH3 antibody, 2510002C21Rik antibody, Ltb4dh antibody, Dig1 antibody, ltb4dh antibody, wu:fj35e05 antibody, zgc:101689 antibody, PTGR1 antibody, prostaglandin reductase 1 antibody, PTGR1 antibody, Ptgr1 antibody, ptgr1 antibody

Background: The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A 4 ), leukotrienes (leukotriene B 4 ) and E/F prostaglandins (15-oxo prostaglandins). The reactions mediated by LTB4DH constitute an important inactivation pathway for these key lipid mediators involved in inflammation. LTB4DH belongs to the medium-chain dehydrogenase/reductase enzyme family.Synonyms: 15-oxoprostaglandin 13-reductase, LTB4DH, NADP-dependent leukotriene B4 12-hydroxydehydrogenase, PGR-1, PGR1, PTGR1

Molecular Weight: approx. 36 kDa

Gene ID: 22949

NCBI Accession: NP_036344

UniProt: Q14914