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PTGR1 antibody (N-Term)

PTGR1 Reactivity: Human, Rat, Rabbit, Horse, Cow, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785929
  • Target See all PTGR1 Antibodies
    PTGR1 (Prostaglandin Reductase 1 (PTGR1))
    Binding Specificity
    • 9
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Rabbit, Horse, Cow, Guinea Pig
    Host
    • 33
    • 1
    • 1
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTGR1 antibody is un-conjugated
    Application
    • 24
    • 23
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VRTKTWTLKK HFVGYPTNSD FELKTSELPP LKNGEVLLEA LFLTVDPYMR
    Predicted Reactivity
    Cow: 93%, Guinea Pig: 83%, Horse: 83%, Human: 93%, Rabbit: 83%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against LTB4DH. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH
    Top Product
    Discover our top product PTGR1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 329 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Vitturi, Chen, Woodcock, Salvatore, Bonacci, Koenitzer, Stewart, Wakabayashi, Kensler, Freeman, Schopfer: "Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25626-37, (2013) (PubMed).

  • Target
    PTGR1 (Prostaglandin Reductase 1 (PTGR1))
    Alternative Name
    LTB4DH (PTGR1 Products)
    Synonyms
    LTB4DH antibody, PGR1 antibody, ZADH3 antibody, 2510002C21Rik antibody, Ltb4dh antibody, Dig1 antibody, ltb4dh antibody, wu:fj35e05 antibody, zgc:101689 antibody, PTGR1 antibody, prostaglandin reductase 1 antibody, PTGR1 antibody, Ptgr1 antibody, ptgr1 antibody
    Background
    LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
    Alias Symbols: MGC34943, PGR1, ZADH3, LTB4DH
    Protein Interaction Partner: PRDX5, PEBP1, ATP6V1A, UBC,
    Protein Size: 329
    Molecular Weight
    36 kDa
    Gene ID
    22949
    NCBI Accession
    NM_012212, NP_036344
    UniProt
    A8K0N2
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