HOXA1 antibody

Catalog No. ABIN499123

This Goat Polyclonal antibody specifically detects HOXA1 in WB and EIA. It exhibits reactivity toward Human, Mouse, Rat, Dog and Pig.

Quick Overview for HOXA1 antibody (ABIN499123)

Target: HOXA1 (Homeobox A1 (HOXA1))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This HOXA1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HOXA1 Antibody

Specificity: This antibody is expected to recognize reported isoforms a and b (NP_005513.1 and, NP_705873.2).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Target Details for HOXA1

Target: HOXA1 (Homeobox A1 (HOXA1))

Alternative Name: HOXA1 / HOX1F

Background: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-1F, Homeobox protein Hox-A1

Gene ID: 3198

NCBI Accession: NP_005513

UniProt: P49639

Pathways: Sensory Perception of Sound