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ARL6IP1 antibody (C-Term)

ARL6IP1 Reactivity: Human, Mouse WB, EIA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499337
  • Target See all ARL6IP1 Antibodies
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Binding Specificity
    • 14
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 38
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    • 4
    Rabbit
    Clonality
    • 36
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARL6IP1 antibody is un-conjugated
    Application
    • 25
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.
    Purification
    Ion exchange chromatography
    Immunogen
    Human ARMER / ARL6IP / AIP1 (C-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product ARL6IP1 Primary Antibody
  • Application Notes
    ELISA. Western Blot: ARMER antibody can be used for detection of ARMER at 0.5 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    Alternative Name
    ARL6IP1 (ARL6IP1 Products)
    Synonyms
    arl6ip antibody, MGC56593 antibody, zgc:56593 antibody, zgc:77873 antibody, ARL6IP antibody, aip1 antibody, armer antibody, ARL6IP1 antibody, MGC85055 antibody, MGC139614 antibody, DKFZp459O112 antibody, AIP1 antibody, ARMER antibody, AIP-6 antibody, AL022945 antibody, AU042858 antibody, Aip-1 antibody, Arl6ip antibody, C85138 antibody, mKIAA0069 antibody, ADP-ribosylation factor-like 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog antibody, ADP-ribosylation factor like GTPase 6 interacting protein 1 antibody, arl6ip1 antibody, ARL6IP1 antibody, arl6ip1.L antibody, Arl6ip1 antibody
    Background
    Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12 (2), other caspases such as caspase-9 are also thought to be activated following ER stress (3). Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, KIAA0069
    Gene ID
    23204
    UniProt
    Q15041
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