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BFAR antibody (C-Term)

BFAR Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499449
  • Target See all BFAR Antibodies
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Binding Specificity
    • 14
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 1
    Rabbit
    Clonality
    • 35
    • 1
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BFAR antibody is un-conjugated
    Application
    • 24
    • 23
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    BFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.
    Isotype
    IgG
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    Discover our top product BFAR Primary Antibody
  • Application Notes
    ELISA. Western Blot: BFAR antibody can be used for detection of BFAR at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Alternative Name
    BFAR / RNF47 (BFAR Products)
    Synonyms
    BFAR antibody, MGC137916 antibody, bfar antibody, BAR antibody, RNF47 antibody, 3010001A07Rik antibody, AI666707 antibody, AW107665 antibody, Bar antibody, Rnf47 antibody, bifunctional apoptosis regulator antibody, bifunctional apoptosis regulator L homeolog antibody, BFAR antibody, bfar.L antibody, bfar antibody, Bfar antibody
    Background
    The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.Synonyms: BAR, Bifunctional apoptosis regulator, RING finger protein 47
    Gene ID
    51283
    NCBI Accession
    NP_057645
    UniProt
    Q9NZS9
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