C1QTNF3 antibody (Intermediate Domain)

Catalog No. ABIN499667

Product Details anti-C1QTNF3 Antibody

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Binding Specificity: Intermediate Domain

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QTNF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: CTRP3 antibody was raised against a 16 amino acid peptide from near the center of human CTRP3.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human CTRP3 / CORS26 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 -2 μg/mL. Mouse heart cell lysate can be used as positive control. These proteins are oftenhighly modified post-translationally and migrate in SDS-PAGE at positions other than theirpredicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for C1QTNF3

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Alternative Name: C1QTNF3 (C1QTNF3 Products)

Synonyms: Amacr antibody, zgc:110704 antibody, C1ATNF3 antibody, CORCS antibody, CORS antibody, CORS-26 antibody, CORS26 antibody, CTRP3 antibody, 2310005P21Rik antibody, Corcs antibody, Cors antibody, C1q and tumor necrosis factor related protein 3 antibody, alpha-methylacyl-CoA racemase antibody, C1q and TNF related 3 antibody, C1QTNF3 antibody, amacr antibody, C1qtnf3 antibody

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).Synonyms: C1ATNF3, CORS26, CTRP3, Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26

Gene ID: 114899

NCBI Accession: NP_852100

UniProt: Q9BXJ4