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IER3 antibody (Center)

IER3 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499960
  • Target See all IER3 Antibodies
    IER3 (Immediate Early Response 3 (IER3))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    Center
    Reactivity
    • 32
    • 19
    • 14
    • 4
    • 4
    • 4
    Human, Mouse
    Host
    • 47
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IER3 antibody is un-conjugated
    Application
    • 36
    • 20
    • 14
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to IEX1.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    IEX1 antibody was raised against a 24 amino acid peptide near the center of human IEX1.
    Isotype
    IgG
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    Discover our top product IER3 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 2 - 4 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    IER3 (Immediate Early Response 3 (IER3))
    Alternative Name
    IER3 / IEX1 (IER3 Products)
    Synonyms
    DIF-2 antibody, DIF2 antibody, GLY96 antibody, IEX-1 antibody, IEX-1L antibody, IEX1 antibody, PRG1 antibody, AI663993 antibody, cI-3 antibody, gly96 antibody, IER3 antibody, Dif2 antibody, Iex1 antibody, Ler3 antibody, Prg1 antibody, immediate early response 3 antibody, IER3 antibody, Ier3 antibody
    Background
    IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappaB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.Synonyms: DIF2, Differentiation-dependent gene 2 protein, GLY96, IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, PRG1, Radiation-inducible immediate-early gene IEX-1
    Gene ID
    8870
    UniProt
    P46695
    Pathways
    Regulation of Carbohydrate Metabolic Process
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