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NAIP antibody (C-Term)

NAIP Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500306
  • Target See all NAIP Antibodies
    NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 4
    • 2
    Human
    Host
    • 31
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAIP antibody is un-conjugated
    Application
    • 26
    • 14
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects NAIP at C-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogen
    NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.
    Isotype
    IgG
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    Discover our top product NAIP Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 to 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))
    Alternative Name
    NAIP (NAIP Products)
    Synonyms
    BIRC1 antibody, NLRB1 antibody, psiNAIP antibody, AV364616 antibody, Birc1a antibody, D13Lsd1 antibody, Naip antibody, Naip-rs1 antibody, NLR family apoptosis inhibitory protein antibody, NLR family, apoptosis inhibitory protein 1 antibody, NAIP antibody, Naip1 antibody
    Background
    Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy (1,2). Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR), these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO (4), suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported (5).Synonyms: BIRC1, Baculoviral IAP repeat-containing protein 1
    Gene ID
    4671
    UniProt
    Q13075
    Pathways
    Apoptosis, Inflammasome
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