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NUP107 antibody (Center)

NUP107 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500393
  • Target See all NUP107 Antibodies
    NUP107 (Nucleoporin 107kDa (NUP107))
    Binding Specificity
    • 16
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 35
    • 22
    • 5
    • 1
    Human, Mouse, Rat
    Host
    • 47
    • 2
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 21
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUP107 antibody is un-conjugated
    Application
    • 46
    • 26
    • 16
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects NUP107 at center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    NUP107 antibody was raised against a 20 amino acid peptide from near the center of human NUP107.
    Isotype
    IgG
    Top Product
    Discover our top product NUP107 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    NUP107 (Nucleoporin 107kDa (NUP107))
    Alternative Name
    NUP107 (NUP107 Products)
    Synonyms
    zgc:152723 antibody, si:dkey-27k7.3 antibody, Afu1g10860 antibody, BcDNA:LD18761 antibody, CG6743 antibody, Dmel\\CG6743 antibody, Nup 107 antibody, Nup170 antibody, dmNup107 antibody, nup107 antibody, SPBC582.11c antibody, AW541137 antibody, C76801 antibody, NUP84 antibody, nucleophosmin/nucleoplasmin 3 antibody, nucleoporin 107 antibody, nuclear pore complex protein Nup107 antibody, Nuclear pore complex protein Nup107 antibody, nucleoporin 107kDa S homeolog antibody, nucleoporin 107kDa antibody, Nucleoporin 107kD antibody, nucleoporin Nup107 antibody, NPM3 antibody, NUP107 antibody, nup107 antibody, AFUA_1G10860 antibody, LOC5563712 antibody, CpipJ_CPIJ003997 antibody, BDBG_00235 antibody, nu107 antibody, nup107.S antibody, Nup107 antibody
    Background
    The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.Synonyms: NUP84, Nuclear pore complex protein Nup107, Nucleoporin Nup107
    Gene ID
    57122
    UniProt
    P57740
    Pathways
    Protein targeting to Nucleus
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