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ZBED1 antibody (Center)

ZBED1 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501137
  • Target See all ZBED1 Antibodies
    ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))
    Binding Specificity
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 33
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 24
    • 9
    Rabbit
    Clonality
    • 26
    • 7
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZBED1 antibody is un-conjugated
    Application
    • 21
    • 12
    • 10
    • 8
    • 4
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ZBED1. The antibody is predicted to have no cross-reactivity to ZBED2 or ZBED3.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Affinity chromatography
    Immunogen
    ZBED1 antibody was raised against a 15 amino acid peptide from near the center of human ZBED1.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))
    Alternative Name
    ZBED1 (ZBED1 Products)
    Synonyms
    ZBED1 antibody, ZBED1P antibody, ALTE antibody, DREF antibody, TRAMP antibody, hDREF antibody, zinc finger BED-type containing 1 antibody, zinc finger, BED-type containing 1 antibody, ZBED1 antibody, zbed1 antibody
    Background
    ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters, anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.Synonyms: ALTE, DREF, KIAA0785, Putative Ac-like transposable element, Zinc finger BED domain-containing protein 1, dREF homolog
    Gene ID
    9189
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