Early Growth Response 3 (EGR3) (Middle Region) antibody

Details for Product No. ABIN501248
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Antigen
Synonyms zgc:92020, EGR-3, PILOT, Pilot
Epitope
Middle Region
(9), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Human
(39), (21), (18), (13), (13), (12), (12)
Host
Rabbit
(38), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(23), (15), (10), (9), (8), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN501248
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human EGR3
Sequence ALPPYSNCGD LYSEPVSFHD PQGNPGLAYS PQDYQSAKPA LDSNLFPMIP
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against EGR3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EGR3
Background EGR3 is a probable transcription factor involved in muscle spindle development.The gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also plays a role in muscle development.
Molecular Weight 42 kDa
Gene ID 1960
NCBI Accession NP_004421, NM_004430
UniProt Q06889
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 387 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Early Growth Response 3 (EGR3) (Middle Region) antibody Immunohistochemistry with Placenta tissue at an antibody concentration of 5µg/ml using anti-EGR3 antibody (ARP34197_P050)
Background publications Yamada, Gerber, Iwayama et al.: "Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2815-20, 2007 (PubMed).

Validation Images
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