You are viewing an incomplete version of our website. Please click to reload the website as full version.

TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody

Details for Product No. ABIN501329, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms tara, DFNB28, TARA, dJ37E16.4, AI428493, EST478828, Tara, mKIAA1662
Epitope
Middle Region
(2), (2), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(21), (6), (6), (1), (1), (1)
Host
Rabbit
(15), (6)
Clonality
Polyclonal
Application
Western Blotting (WB)
(19), (10), (3), (3), (3), (1)
Pubmed 1 reference available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the middle region of human TRIOBP
Blocking Peptide Blocking peptide for this product available: ABIN985595
Sequence QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL
Predicted Reactivity Horse : 100 %, Human : 100 %, Bovine : 90 %, Chicken : 90 %, Dog : 90 %, Mouse : 90 %, Rabbit : 90 %, Guinea pig : 90 %, Rat : 80 %, African clawed frog : 80 %
Characteristics This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TRIOBP (TRIOBP Antibody Abstract)
Background TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Molecular Weight 47 kDa
Gene ID 11078
NCBI Accession NP_619538, NM_138632
UniProt A6NID1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 431 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody (ABIN501329) anti-TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody
Immunohistochemistry (IHC) image for anti-TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody (ABIN501329) anti-TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody (Image 2)
Background publications Yu, Lan, Zhu et al.: "The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara." in: Biochemical and biophysical research communications, Vol. 367, Issue 4, pp. 805-12, 2008 (PubMed).

Catalog No. ABIN501329
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)