TRIO and F-Actin Binding Protein (TRIOBP) (Middle Region) antibody

Details for Product No. ABIN501329
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms tara, DFNB28, TARA, dJ37E16.4, AI428493, EST478828, Tara, mKIAA1662
Epitope
Middle Region
(2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Xenopus laevis, Human, Chicken
(16), (4), (4), (1), (1), (1)
Host
Rabbit
(11), (5)
Clonality
Polyclonal
Application
Western Blotting (WB)
(15), (7), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN501329
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the middle region of human TRIOBP
Sequence QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL
Predicted Reactivity Horse : 100 %, Human : 100 %, Bovine : 90 %, Chicken : 90 %, Dog : 90 %, Mouse : 90 %, Rabbit : 90 %, Guinea pig : 90 %, Rat : 80 %, African clawed frog : 80 %
Characteristics This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TRIOBP
Background TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Molecular Weight 47 kDa
Gene ID 11078
NCBI Accession NP_619538, NM_138632
UniProt A6NID1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 431 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Yu, Lan, Zhu et al.: "The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara." in: Biochemical and biophysical research communications, Vol. 367, Issue 4, pp. 805-12, 2008 (PubMed).

Validation Images
Did you look for something else?
back to top