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TRIOBP antibody (Middle Region)

TRIOBP Reactivity: Human, Mouse, Rat, Horse, Guinea Pig, Rabbit, Cow, Dog, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501329
  • Target See all TRIOBP Antibodies
    TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse, Guinea Pig, Rabbit, Cow, Dog, Pig
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 8
    This TRIOBP antibody is un-conjugated
    Application
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP
    Top Product
    Discover our top product TRIOBP Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 431 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
    Alternative Name
    TRIOBP (TRIOBP Products)
    Synonyms
    tara antibody, DFNB28 antibody, TARA antibody, dJ37E16.4 antibody, AI428493 antibody, EST478828 antibody, Tara antibody, mKIAA1662 antibody, TRIO and F-actin binding protein antibody, TRIO and F-actin-binding protein antibody, TRIO and F-actin binding protein L homeolog antibody, TRIO and F-actin binding protein-like antibody, TRIOBP antibody, LOC100354753 antibody, triobp.L antibody, TRIOBPL antibody, Triobp antibody
    Background
    TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
    Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
    Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
    Protein Size: 431
    Molecular Weight
    47 kDa
    Gene ID
    11078
    NCBI Accession
    NM_138632, NP_619538
    UniProt
    Q9H2D6
    Pathways
    Regulation of Actin Filament Polymerization
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