TRIOBP antibody

Catalog No. ABIN931150

This Mouse Monoclonal antibody specifically detects TRIOBP in WB and DB. It exhibits reactivity toward Human.

Quick Overview for TRIOBP antibody (ABIN931150)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIOBP antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Clone: 2438C1a

Product Details anti-TRIOBP Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: TRIOBP antibody was raised in mouse using recombinant Human Trio And F-Actin Binding Protein

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: TRIOBP antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIOBP

Background: This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a Cterminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). Synonyms: Monoclonal TRIOBP antibody, Anti-TRIOBP antibody, TRIO and F-actin binding protein antibody, TARA antibody, DFNB28 antibody, FLJ39315 antibody, KIAA1662 antibody, dJ37E16.4 antibody, HRIHFB2122 antibody.

Pathways: Regulation of Actin Filament Polymerization