KCNA10 antibody (N-Term)
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- Target See all KCNA10 Antibodies
- KCNA10 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 10 (KCNA10))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNA10 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DVCGWKEMEV ALVNFDNSDE IQEEPGYATD FDSTSPKGRP GGSSFSNGKI
- Predicted Reactivity
- Cow: 92%, Dog: 79%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against KCNA10. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KCNA10
- Top Product
- Discover our top product KCNA10 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 511 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KCNA10 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 10 (KCNA10))
- Alternative Name
- KCNA10 (KCNA10 Products)
- Synonyms
- cKv1.2 antibody, Kcn1 antibody, Kv1.8 antibody, Gm1962 antibody, Kcna8 antibody, potassium voltage-gated channel subfamily A member 10 antibody, potassium voltage-gated channel, shaker-related subfamily, member 10 antibody, KCNA10 antibody, Kcna10 antibody
- Background
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KCNA10 is a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
Alias Symbols: Kcn1, Kv1.8
Protein Interaction Partner: POMP,
Protein Size: 511 - Molecular Weight
- 58 kDa
- Gene ID
- 3744
- NCBI Accession
- NM_005549, NP_005540
- UniProt
- Q16322
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