Potassium Channel, Subfamily K, Member 4 (KCNK4) (N-Term) antibody

Details for Product No. ABIN501409, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms K2p4.1, TRAAK, TRAAK1, MLZ-622, TRAAKt, Tex40, KT4.1
Epitope
N-Term
(7), (5), (2), (1), (1)
Reactivity
Cow (Bovine), Human
(24), (13), (4), (1)
Host
Rabbit
(24)
Clonality
Polyclonal
Application
Western Blotting (WB)
(21), (13), (4)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human KCNK4
Blocking Peptide Blocking peptide for this product available: Potassium Channel, Subfamily K, Member 4 (KCNK4) (N-Term) peptide (ABIN978813)
Sequence MRSTTLLALL ALVLLYLVSG ALVFRALEQP HEQQAQRELG EVREKFLRAH
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Pig : 100 %, Guinea pig : 70 %
Characteristics This is a rabbit polyclonal antibody against KCNK4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KCNK4 (KCNK4 Antibody Abstract)
Background Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. KCNK4 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. It homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
Molecular Weight 43 kDa
Gene ID 50801
NCBI Accession NM_033310, NP_201567
UniProt Q9NYG8
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 393 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Potassium Channel, Subfamily K, Member 4 (KCNK4) (N-Term) antibody (ABIN501409) WB Suggested Anti-KCNK4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: Bogdan, Fitzgibbon, Woolverton et al.: "5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques." in: Neuroscience letters, Vol. 503, Issue 2, pp. 83-6, 2011 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Catalog No. ABIN501409
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)