KCNK4 antibody (N-Term)

Catalog No. ABIN2784082

There is 1 publication for this product available. The Rabbit Polyclonal anti-KCNK4 antibody is suitable to detect KCNK4 in samples from Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for KCNK4 antibody (N-Term) (ABIN2784082)

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNK4 Antibody

Binding Specificity: N-Term

Purpose: KCNK4 Antibody - N-terminal region

Sequence: ELGEVREKFL RAHPCVSDQE LGLLIKEVAD ALGGGADPET NSTSNSSHSA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KCNK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNK4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108632

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KCNK4 antibody (ABIN2784082)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Alternative Name: KCNK4

Background:

Background Information: Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. KCNK4 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. It homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Potassium channel, subfamily K, member 4

Alternative Symbols: FHEIG, TRAAK, K2p4.1, TRAAK1

Protein Name: Potassium channel subfamily K member 4

Molecular Weight: 43 kDa

Gene ID: 50801

NCBI Accession: NP_201567

UniProt: Q9NYG8