Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Middle Region) antibody

Details for Product No. ABIN502354
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Antigen
Synonyms Mir, mylip, wu:fj36b03, zgc:55987, MYLIP, mir, IDOL, MIR, 9430057C20Rik
Epitope
Middle Region
(3), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Xenopus laevis, Human, Chicken
(35), (24), (21), (12), (12), (12)
Host
Rabbit
(32), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(25), (17), (16), (10), (7), (5), (1)
Pubmed 1 reference available
Quantity 50 μg
Options
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Catalog No. ABIN502354
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human MYLIP
Sequence CSSCEGLSCQ QTRVLQEKLR KLKEAMLCMV CCEEEINSTF CPCGHTVCCE
Predicted Reactivity Human : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Dog : 90 %, Guinea pig : 90 %, Horse : 90 %, Rabbit : 90 %, Chicken : 80 %, Pig : 80 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against MYLIP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name MYLIP
Background The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowthThe ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.
Molecular Weight 50 kDa
Gene ID 29116
NCBI Accession NM_013262, NP_037394
UniProt Q8WY64
Research Area Chromatin and Nuclear Signaling, Cell Cycle, Proteolysis / Ubiquitin, Cytoskeleton
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 445 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Middle Region) antibody WB Suggested Anti-MYLIP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: SK-MEL-2 cell lysate
Background publications Ohmura-Hoshino, Matsuki, Aoki et al.: "Inhibition of MHC class II expression and immune responses by c-MIR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 1, pp. 341-54, 2006 (PubMed).

Validation Images
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