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Details for Product No. ABIN502515

Der1-Like Domain Family, Member 3 (DERL3) (C-Term) antibody

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Synonyms 1810006I20Rik, 1810063P04Rik, IZP6, derlin-3, C22orf14, LLN2, zgc:63991
»Alternatives C-Term
»Alternatives Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine), Dog (Canine), Human, Chicken
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN502515
Quantity 50 µg
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-DERL3 antibody: synthetic peptide directed towards the C terminal of human DERL3
Predicted Reactivity Bovine : 100%, Chicken : 100%, Dog : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%, Zebrafish : 100%, Horse : 85%
Characteristics This is a rabbit polyclonal antibody against DERL3. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name DERL3
Background DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).
Molecular Weight 27kDa
Gene ID 91319
NCBI Accession NP_001002862, NM_001002862
UniProt Q96Q80
Research Area Signaling
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-DERL3 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Morrison, Lööf, He et al.: "Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population." in: The Journal of cell biology, Vol. 172, Issue 3, pp. 433-40, 2006 (PubMed).

Alternatives for antigen "Der1-Like Domain Family, Member 3 (DERL3)", type "Antibodies"
Hosts (20)
Reactivities (17), (1)
Applications (19), (13), (8), (4), (2)
Epitopes (12), (1), (1), (1)