Protocadherin 1 (PCDH1) (N-Term) antibody

Details for Product No. ABIN502613
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Antigen
Synonyms PC42, PCDH42, 2010005A06Rik, AI585920, PCDH-1, axpc, protocadherin-1
Epitope
N-Term
(11), (8), (8), (6), (2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Xenopus laevis, Human, Chicken
(50), (16), (16), (13), (13), (13)
Host
Rabbit
(35), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunocytochemistry (ICC)
(40), (24), (15), (14), (11), (10), (8), (8), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN502613
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PCDH1
Sequence LLPSMLLALL LLLAPSPGHA TRVVYKVPEE QPPNTLIGSL AADYGFPDVG
Predicted Reactivity Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Bovine : 90 %, Chicken : 90 %, Guinea pig : 90 %
Characteristics This is a rabbit polyclonal antibody against PCDH1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PCDH1
Background PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. It is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity.This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Molecular Weight 111 kDa
Gene ID 5097
NCBI Accession NP_002578, NM_002587
UniProt Q08174
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1060 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Protocadherin 1 (PCDH1) (N-Term) antibody WB Suggested Anti-PCDH1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate
anti-Protocadherin 1 (PCDH1) (N-Term) antibody (2) anti-Protocadherin 1 (PCDH1) (N-Term) antibody (Image 2)
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Validation Images
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