IFRD1 antibody (AA 1-300)
-
- Target See all IFRD1 Antibodies
- IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))
-
Binding Specificity
- AA 1-300
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IFRD1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Protein A Chromatography
- Immunogen
- A partial length recombinant Tis7 protein (amino acids 1-300) was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product IFRD1 Primary Antibody
-
-
- Application Notes
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
- Target
- IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))
- Alternative Name
- Tis7 (IFRD1 Products)
- Synonyms
- im:7067566 antibody, si:dkey-192l17.2 antibody, wu:fi35f04 antibody, wu:fj67a06 antibody, zgc:154080 antibody, IFR1 antibody, PC4 antibody, TIS7 antibody, Ifnl antibody, Tis7 antibody, Pc4 antibody, interferon-related developmental regulator 1 antibody, interferon related developmental regulator 1 L homeolog antibody, interferon related developmental regulator 1 antibody, ifrd1 antibody, ifrd1.L antibody, IFRD1 antibody, Ifrd1 antibody
- Background
- Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.
- Molecular Weight
- 55 kDa
- Gene ID
- 3475
- UniProt
- O00458
-