ABCB1 antibody (Middle Region)

Catalog No. ABIN503227

This Rabbit Polyclonal antibody specifically detects ABCB1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Sheep, Pig, Guinea Pig and Cow.

Quick Overview for ABCB1 antibody (Middle Region) (ABIN503227)

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Zebrafish (Danio rerio), Sheep, Pig, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ABCB1 Antibody

Binding Specificity: Middle Region

Sequence: AIVPIIAIAG VVEMKMLSGQ ALKDKKELEG SGKIATEAIE NFRTVVSLTQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ABCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCB1

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Alternative Name: ABCB1

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct
Alias Symbols: ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-gp, PGY1, P-GP
Protein Interaction Partner: FBXO15, UBA7, UBC, MAPKAP1, BCCIP, CD4, LNX1, PSMB8, PIM1, DHX9, HAX1, RNF2, CAV1,
Protein Size: 1280

Molecular Weight: 141 kDa

Gene ID: 5243

NCBI Accession: NM_000927, NP_000918

UniProt: P08183