MTO1 (N-Term) antibody

Details for Product No. ABIN503584
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Antigen
Synonyms 2310039H01Rik, 5730419A02Rik, COXPD10
Epitope
N-Term
(3), (1)
Reactivity
Rabbit, Mouse (Murine), Cow (Bovine), Dog (Canine), Human, Chicken
(9), (2), (2)
Host
Rabbit
(8)
Clonality
Polyclonal
Application
Western Blotting (WB)
(8), (6), (3), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN503584
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human MTO1
Sequence STVYAESVIL TTGTFLRGMI VIGLETHPAG RLGDQPSIGL AQTLEKLGFV
Predicted Reactivity Chicken : 100 %, Human : 100 %, Bovine : 90 %, Dog : 90 %, Guinea pig : 90 %, Horse : 90 %, Mouse : 90 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against MTO1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Background MTO1 is a mitochondrial protein thought to be involved in mitochondrial tRNA modification. It may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene.This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 81 kDa
Gene ID 25821
NCBI Accession NP_001116698, NM_001123226
UniProt Q9Y2Z2
Research Area Chromatin and Nuclear Signaling, DNA/RNA, Organelles
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 732 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-MTO1 (N-Term) antibody WB Suggested Anti-MTO1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle
Background publications Krull, Brosius, Schmitz: "Alu-SINE exonization: en route to protein-coding function." in: Molecular biology and evolution, Vol. 22, Issue 8, pp. 1702-11, 2005 (PubMed).

Validation Images
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