Pim-1 Oncogene (PIM1) (N-Term) antibody

Details for Product No. ABIN503951
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Antigen
Synonyms cb1068, fj47b05, pim2, wu:fj47b05, PIM1, pim, pim-1, pim3, LON, LONP, LonHS, PRSS15, hLON, PIM, Pim-1
Epitope
N-Term
(19), (14), (11), (10), (10), (8), (7), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(138), (63), (63), (37), (36), (36), (24), (24), (1)
Host
Rabbit
(112), (31), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2)
Application
Western Blotting (WB)
(89), (71), (50), (30), (17), (16), (11), (6), (5), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN503951
289.00 $
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  • +1 404 474 4654
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Immunogen Synthetic peptide directed towards the N terminal of human PIM1
Sequence MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Sheep : 100 %, Guinea pig : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PIM1
Background PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Molecular Weight 36 kDa
Gene ID 5292
NCBI Accession NM_002648, NP_002639
Research Area Cancer, Hematopoietic Progenitors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 313 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Pim-1 Oncogene (PIM1) (N-Term) antibody WB Suggested Anti-PIM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate
Background publications Wernig, Gonneville, Crowley et al.: "The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes." in: Blood, Vol. 111, Issue 7, pp. 3751-9, 2008 (PubMed).

Validation Images
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