anti-PIM1 antibody (Pim-1 Oncogene) (N-Term)

Details for Product anti-PIM1 Antibody No. ABIN503951, Supplier: Login to see New
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Antigen
Synonyms cb1068, fj47b05, pim2, wu:fj47b05, PIM1, pim, pim-1, pim3, LON, LONP, LonHS, PRSS15, hLON, PIM, Pim-1
Epitope
N-Term
(38), (24), (18), (15), (13), (12), (10), (10), (9), (9), (6), (5), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(171), (51), (50), (2), (1), (1), (1), (1)
Host
Rabbit
(131), (53), (5)
Clonality
Polyclonal
Conjugate
This PIM1 antibody is un-conjugated
(11), (8), (5), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(123), (108), (52), (43), (28), (13), (7), (7), (6), (6), (6), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human PIM1
Sequence MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Sheep : 100 %, Guinea pig : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PIM1 (PIM1 Antibody Abstract)
Background PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Molecular Weight 36 kDa
Gene ID 5292
NCBI Accession NM_002648, NP_002639
Research Area Cancer, Hematopoietic Progenitors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 313 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-PIM1 antibody (Pim-1 Oncogene) (N-Term) (ABIN503951) WB Suggested Anti-PIM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Wernig, Gonneville, Crowley et al.: "The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes." in: Blood, Vol. 111, Issue 7, pp. 3751-9, 2008 (PubMed).

Catalog No. ABIN503951
$289.00
Plus shipping costs $45.00

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