PIM1 antibody

Catalog No. ABIN7269375

The Rabbit Monoclonal anti-PIM1 antibody (ABIN7269375) specifically detects PIM1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for PIM1 antibody (ABIN7269375)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PIM1 Antibody

Purpose: PIM1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PIM1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Alternative Name: PIM1

Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],PIM,PIM1,PIM1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Chromatin Remodeling,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Phosphorylation,Epigenetics & Nuclear Signaling,Hematopoietic Progenitors,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Signal Transduction,Stem Cells,PIM1

Molecular Weight: 35kDa/45kDa

Gene ID: 5292

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process