Plastin 3 (PLS3) (Middle Region) antibody

Details for Product No. ABIN504028
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Antigen
Synonyms MGC68681, t-plastin, MGC106020, DKFZp459D0939, T-plastin, AI115446, AL024105, T-fimbrin, PLS3, Plastin-3
Epitope
Middle Region
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(31), (17), (16), (12), (12), (12)
Host
Rabbit
(30), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(20), (15), (10), (9), (6), (5), (2), (2)
Pubmed 1 reference available
Quantity 50 µg
Options
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Catalog No. ABIN504028
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PLS3
Sequence RRYTLNVLED LGDGQKANDD IIVNWVNRTL SEAGKSTSIQ SFKDKTISSS
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 90 %, Guinea pig : 90 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against PLS3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PLS3
Background Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as
Molecular Weight 71 kDa
Gene ID 5358
NCBI Accession NP_005023, NM_005032
UniProt P13797
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 630 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Plastin 3 (PLS3) (Middle Region) antibody WB Suggested Anti-PLS3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HT1080 cell lysate
anti-Plastin 3 (PLS3) (Middle Region) antibody (2) WB Suggested Anti-PLS3
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500
Positive Control: HT1080 cell lysate
PLS3 is supported by BioGPS gene expression data to be expressed in HT1080
Background publications Oprea, Kröber, McWhorter et al.: "Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy." in: Science (New York, N.Y.), Vol. 320, Issue 5875, pp. 524-7, 2008 (PubMed).

Validation Images
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