Regulator of G-Protein Signaling 11 (RGS11) (Middle Region) antibody

Details for Product No. ABIN504607
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Antigen
Synonyms RS11, C78048, XRGSIV, rgs9-a
Epitope
Middle Region
(7), (7), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Dog (Canine), Pig (Porcine), Human, Chicken
(19), (1), (1)
Host
Rabbit
(16), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(19), (6), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN504607
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human RGS11
Sequence LRQPHRYVLD DAQLHIYMLM KKDSYPRFLK SDMYKALLAE AGIPLEMKRR
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against RGS11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RGS11
Background RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Molecular Weight 51 kDa
Gene ID 8786
NCBI Accession NM_003834, NP_003825
UniProt Q4TT72
Research Area Signaling, Immunology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 446 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Regulator of G-Protein Signaling 11 (RGS11) (Middle Region) antibody WB Suggested Anti-RGS11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: 293T cell lysate
Background publications Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Validation Images
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