GNAQ antibody (AA 101-200)

Catalog No. ABIN516106

This Mouse Monoclonal antibody specifically detects GNAQ in WB and ELISA. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for GNAQ antibody (AA 101-200) (ABIN516106)

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GNAQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3B9

Product Details anti-GNAQ Antibody

Binding Specificity: AA 101-200

Purpose: Mouse monoclonal antibody raised against a partial recombinant GNAQ.

Sequence: YKYEHNKAHA QLVREVDVEK VSAFENPYVD AIKSLWNDPG IQECYDRRRE YQLSDSTKYY LNDLDRVADP AYLPTQQDVL RVRVPTTGII EYPFDLQSVI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GNAQ (NP_002063.2, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GNAQ antibody (ABIN516106)

Sánchez-Fernández, Cabezudo, Caballero, García-Hoz, Tall, Klett, Michnick, Mayor, Ribas: "Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9513-25, (2016) (PubMed).

Target Details for GNAQ

Target: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Alternative Name: GNAQ

Background: Full Gene Name: guanine nucleotide binding protein (G protein), q polypeptide
Synonyms: G-ALPHA-q,GAQ

Gene ID: 2776

NCBI Accession: NM_002072

Pathways: JAK-STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction