MED17 antibody (AA 551-651)

Catalog No. ABIN522887

There is 1 publication for this product available. The Mouse Monoclonal anti-MED17 antibody is suitable to detect MED17 in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for MED17 antibody (AA 551-651) (ABIN522887)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1B5

Product Details anti-MED17 Antibody

Binding Specificity: AA 551-651

Purpose: Mouse monoclonal antibody raised against a partial recombinant CRSP6.

Sequence: FSNHVGLGPI ESIGNASAIT VASPSGDYAI SVRNGPESGS KIMVQFPRNQ CKDLPKSDVL QDNKWSHLRG PFKEVQWNKM EGRNFVYKME LLMSALSPCL L

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CRSP6 (AAH21101, 551 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MED17 antibody (ABIN522887)

Tsutsui, Fukasawa, Shinmyouzu, Nakagawa, Tobe, Tanaka, Ohkuma: "Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 20955-65, (2013) (PubMed).

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background: Full Gene Name: mediator complex subunit 17
Synonyms: CRSP6,CRSP77,DRIP80,FLJ10812,TRAP80

Gene ID: 9440

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha