RASA4 antibody (Middle Region)

Catalog No. ABIN5516667

Product Details anti-RASA4 Antibody

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEGWFRLQPD QSKSRRHDEG NLGSLQLEVR LRDETVLPSS YYQPLVHLLC

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RASA4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASA4

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Alternative Name: RASA4 (RASA4 Products)

Synonyms: CAPRI antibody, GAPL antibody, AA793972 antibody, AW112107 antibody, BB079060 antibody, mKIAA0538 antibody, RAS p21 protein activator 4 antibody, RASA4 antibody, Rasa4 antibody

Background: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: GAPL, CAPRI,

Protein Size: 803

Gene ID: 10156

NCBI Accession: NM_001079877, NP_001073346

UniProt: O43374