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HBG2 antibody (C-Term)
HBG2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HBG2 Antibody
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Target
See all HBG2 Antibodies
HBG2
(Hemoglobin, gamma G (HBG2))
Binding Specificity
All epitopes for HBG2 antibodies
C-Term
Reactivity
All reactivities for HBG2 antibodies
Human
Host
All hosts for HBG2 antibodies
Rabbit
Clonality
All clonalities for HBG2 antibodies
Polyclonal
Conjugate
All conjugates for HBG2 antibodies
This HBG2 antibody is un-conjugated
Application
All applications for HBG2 antibodies
Western Blotting (WB)
Sequence
KLHVDPENFK LLGNVLVTVL AIHFGKEFTP EVQASWQKMV TGVASALSSR
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human HBG2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for HBG2
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Target
HBG2
(Hemoglobin, gamma G (HBG2))
Alternative Name
HBG2 (HBG2 Products )
Synonyms
TNCY antibody, hbb2 antibody, MGC88976 antibody, HBG antibody, hemoglobin subunit gamma 2 antibody, hemoglobin subunit gamma 2 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma 2 S homeolog antibody, HBG2 antibody, hbg2 antibody, hbg2.L antibody, hbg2.S antibody
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. Alias Symbols: TNCY, HBG-T1, Protein Size: 167
Gene ID
3048
NCBI Accession
NM_000184 , NP_000175
UniProt
P69892
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