C1QL3 antibody (Middle Region)

Catalog No. ABIN5517812

Product Details anti-C1QL3 Antibody

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VPKIAFYAGL KRQHEGYEVL KFDDVVTNLG NHYDPTTGKF TCSIPGIYFF

Characteristics: This is a rabbit polyclonal antibody against C1QL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human C1QL3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1QL3

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Alternative Name: C1QL3 (C1QL3 Products)

Synonyms: 1110065A22Rik antibody, AI661623 antibody, C1ql antibody, C1qtnf13 antibody, CTRP13 antibody, K100 antibody, C1QTNF13 antibody, zgc:77412 antibody, C1q-like 3 antibody, complement C1q like 3 antibody, complement component 1, q subcomponent-like 3b antibody, C1ql3 antibody, C1QL3 antibody, c1ql3b antibody

Background: C1QL3 may regulate the number of excitatory synapses that are formed on hippocampus neurons. It has no effect on inhibitory synapses . It plays a role in glucose homeostasis. Via AMPK signaling pathway, C1QL3 stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, C1QL3 reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production.

Alias Symbols: C1QL3, CTRP13,

Protein Interaction Partner: SERPINH1,

Protein Size: 255

Gene ID: 389941

NCBI Accession: NP_001010908

UniProt: Q5VWW1