ABCB5 antibody (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5) (Internal Region)

Details for Product anti-ABCB5 Antibody No. ABIN5553417, Supplier: Log in to see
Antigen
  • MDR1
  • wu:fi81f06
  • mdr1
  • im:7158730
  • wu:fc18f02
  • ABCB5alpha
  • ABCB5beta
  • EST422562
  • 9230106F14Rik
  • RGD1566342
  • ABCB5
  • ATP-binding cassette, sub-family B (MDR/TAP), member 5
  • ATP-binding cassette sub-family B member 5
  • ATP-binding cassette, subfamily B (MDR/TAP), member 5
  • multidrug resistance protein 1-like
  • ABCB5
  • abcb5
  • TGME49_049820
  • PAAG_04387
  • VDBG_00160
  • VDBG_02292
  • Abcb5
  • LOC536724
Epitope
Internal Region
34
21
12
12
11
6
2
2
1
1
1
1
Reactivity
Human
113
18
6
2
2
1
Host
Goat
61
28
22
2
Clonality
Polyclonal
Conjugate
This ABCB5 antibody is un-conjugated
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
73
57
48
44
41
39
36
4
2
1
1
1
1
Options
Supplier
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Immunogen Peptide with sequence from the internal region of the protein sequence according to NP_848654.3 and NP_001157413.1. Genename: ABCB5
Sequence C-QTQHRNTSKK AQ
Specificity This antibody is expected to recognize both reported isoforms of Human ABCB5 (NP_848654.3 and NP_001157413.1)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name ABCB5 (ABCB5 Antibody Abstract)
Background ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.Synonyms: ATP-binding cassette sub-family B member 5
Molecular Weight 89.8kDa according to NP_848654.3.
Gene ID 340273
NCBI Accession NP_001157413
UniProt Q2M3G0
Application Notes Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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