FAIM antibody (Internal Region)
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- Target See all FAIM Antibodies
- FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This FAIM antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody reacts to all reported isoforms of FAIM1.
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogen
- Peptide with sequence C-KKYMEDRSKTTN, from the internal region of the protein sequence
- Top Product
- Discover our top product FAIM Primary Antibody
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- Application Notes
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Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
- Alternative Name
- FAIM (FAIM Products)
- Synonyms
- FAIM1 antibody, FAIM antibody, faim antibody, zgc:92712 antibody, zgc:92723 antibody, Fas apoptotic inhibitory molecule antibody, Fas apoptotic inhibitory molecule L homeolog antibody, Fas apoptotic inhibitory molecule b antibody, Fas apoptotic inhibitory molecule a antibody, FAIM antibody, Faim antibody, faim antibody, faim.L antibody, Tsp_00038 antibody, faimb antibody, faima antibody
- Background
- FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1
- Gene ID
- 55179, 9606
- UniProt
- Q9NVQ4
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