C16orf22 antibody, Fbl16 antibody, c380A1.1 antibody, BC042620 antibody, Scirr1 antibody, VIER F-box proteine 2 antibody, F-box and leucine rich repeat protein 16 antibody, fbxl16, putative antibody, F-box and leucine-rich repeat protein 16 antibody, VIER F-box protein 2 antibody, FBXL16 antibody, Smp_174380 antibody, fbxl16 antibody, Fbxl16 antibody, VFB2 antibody
Background
FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.Synonyms: C16orf22, F-box and leucine-rich repeat protein 16, F-box/LRR-repeat protein 16, FBL16