MINA antibody (N-Term)

Catalog No. ABIN500284

Product Details anti-MINA Antibody

Target: MINA (MYC Induced Nuclear Antigen (MINA))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MINA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinty chromatography

Immunogen: MINA antibody was raised against a 15 amino acid peptide near the amino terminus of human MINA.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for MINA

Target: MINA (MYC Induced Nuclear Antigen (MINA))

Alternative Name: MYC-Induced Nuclear Antigen (MINA Products)

Synonyms: MDIG antibody, MINA53 antibody, NO52 antibody, ROX antibody, 1810047J07Rik antibody, 2410057H13Rik antibody, 3830408E23Rik antibody, AI449204 antibody, Mina53 antibody, mina antibody, MGC83527 antibody, MINA antibody, DKFZp459K0725 antibody, Mina antibody, ribosomal oxygenase 2 antibody, MYC induced nuclear antigen antibody, ribosomal oxygenase 2 L homeolog antibody, RIOX2 antibody, Riox2 antibody, MINA antibody, riox2.L antibody, riox2 antibody

Background: MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.Synonyms: MDIG, MINA, MINA53, Mineral dust-induced gene protein, NO52, Nucleolar protein 52

Gene ID: 84864

NCBI Accession: NP_694822

UniProt: Q8IUF8