MINA antibody (C-Term)
Quick Overview for MINA antibody (C-Term) (ABIN6972360)
Target
See all MINA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Characteristics
- MINA (MYC Induced Nuclear Antigen) is an oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated Lys-9 on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on His-39. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. MINA antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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Purification
- Affinity Purified
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Immunogen
- This antibody was raised against a peptide within the C-terminal region of human MINA.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- MINA (MYC Induced Nuclear Antigen (MINA))
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Alternative Name
- MINA
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Molecular Weight
- 55 kDa
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NCBI Accession
- NP_694822
Target
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