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CUL9 antibody (C-Term)

CUL9 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500449
  • Target See all CUL9 Antibodies
    CUL9 (Cullin 9 (CUL9))
    Binding Specificity
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 18
    • 7
    • 2
    • 2
    Human, Mouse
    Host
    • 15
    • 4
    Rabbit
    Clonality
    • 15
    • 4
    Polyclonal
    Conjugate
    • 19
    This CUL9 antibody is un-conjugated
    Application
    • 18
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Cullin-9.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    PARC antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human PARC.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot. Immuncytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CUL9 (Cullin 9 (CUL9))
    Alternative Name
    Cullin-9 (CUL9 Products)
    Synonyms
    H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, parc antibody, 1810035I07Rik antibody, Cul-9 antibody, Parc antibody, mKIAA0708 antibody, RGD1562008 antibody, cullin-9 antibody, cullin 9 antibody, cullin-9 antibody, CUL9 antibody, LOC100083225 antibody, cul9 antibody, LOC100561099 antibody, Cul9 antibody
    Background
    The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.Synonyms: CUL-9, H7AP1, KIAA0708, PARC, UbcH7-associated protein 1, p53-associated parkin-like cytoplasmic protein
    Gene ID
    23113
    NCBI Accession
    NP_055904
    UniProt
    Q8IWT3
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