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CUL9 antibody (C-Term)

CUL9 Reactivity: Human, Mouse WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990433
  • Target See all CUL9 Antibodies
    CUL9 (Cullin 9 (CUL9))
    Binding Specificity
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 18
    • 7
    • 2
    • 2
    Human, Mouse
    Host
    • 15
    • 4
    Rabbit
    Clonality
    • 15
    • 4
    Polyclonal
    Conjugate
    • 19
    This CUL9 antibody is un-conjugated
    Application
    • 18
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Purification
    PARC Antibody is affinity chromatography purified via peptide column.
    Immunogen
    PARC antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PARC. The immunogen is located within the last 50 amino acids of PARC.
    Isotype
    IgG
    Top Product
    Discover our top product CUL9 Primary Antibody
  • Application Notes
    PARC antibody can be used for the detection of PARC by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PARC Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    PARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CUL9 (Cullin 9 (CUL9))
    Alternative Name
    PARC (CUL9 Products)
    Synonyms
    H7AP1 antibody, PARC antibody, RP3-330M21.2 antibody, parc antibody, 1810035I07Rik antibody, Cul-9 antibody, Parc antibody, mKIAA0708 antibody, RGD1562008 antibody, cullin-9 antibody, cullin 9 antibody, cullin-9 antibody, CUL9 antibody, LOC100083225 antibody, cul9 antibody, LOC100561099 antibody, Cul9 antibody
    Background
    PARC Antibody: The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.
    Gene ID
    23113
    NCBI Accession
    NP_055904
    UniProt
    Q8IWT3
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