PLEKHM2
Reactivity: Human
ELISA, WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody (in aliquots) at -20 °C.
Target
PLEKHM2
(Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
zgc:194971 antibody, RP11-169K16.1 antibody, SKIP antibody, 2310034J19Rik antibody, AI854247 antibody, mKIAA0842 antibody, pleckstrin homology and RUN domain containing M2 antibody, pleckstrin homology domain containing, family M (with RUN domain) member 2 antibody, PLEKHM2 antibody, plekhm2 antibody, Plekhm2 antibody
Background
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.Synonyms: KIAA0842, PH domain-containing family M member 2, Pleckstrin homology domain-containing family M member 2, SKIP, Salmonella-induced filaments A and kinesin-interacting protein, SifA and kinesin-interacting protein