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TNFRSF1A antibody (Internal Region)
TNFRSF1A
Reactivity: Human, Rat, Pig
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-TNFRSF1A Antibody
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Target
See all TNFRSF1A Antibodies
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Binding Specificity
All epitopes for TNFRSF1A antibodies
Internal Region
Reactivity
All reactivities for TNFRSF1A antibodies
Human, Rat, Pig
Host
All hosts for TNFRSF1A antibodies
Goat
Clonality
All clonalities for TNFRSF1A antibodies
Polyclonal
Conjugate
All conjugates for TNFRSF1A antibodies
This TNFRSF1A antibody is un-conjugated
Application
All applications for TNFRSF1A antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-SDHEIDRLEL QNGR
Cross-Reactivity (Details)
Species reactivity (expected):Rat, Porcine. Species reactivity (tested):Human.
Purification
Affinity Chromatography
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_001056.1. Genename: TNFRSF1A
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Discover our top product TNFRSF1A Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
0.02 % Sodium Azide 0.2 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TNFRSF1A
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Target
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Alternative Name
CD120a / TNFR1 (TNFRSF1A Products )
Synonyms
CD120a antibody, FPF antibody, MS5 antibody, TBP1 antibody, TNF-R antibody, TNF-R-I antibody, TNF-R55 antibody, TNFAR antibody, TNFR1 antibody, TNFR1-d2 antibody, TNFR55 antibody, TNFR60 antibody, p55 antibody, p55-R antibody, p60 antibody, TNF-R1 antibody, TNF-alphaR1 antibody, TNFRI antibody, TNFRp55 antibody, TNFalpha-R1 antibody, Tnfr-2 antibody, Tnfr1 antibody, fpf antibody, tbp1 antibody, p55-r antibody, tnf-r antibody, tnfar antibody, tnfr1 antibody, cd120a antibody, tnfr55 antibody, tnfr60 antibody, xtnfr1 antibody, wu:fj65b10 antibody, zgc:85914 antibody, TNFR I antibody, TNFRSF1A antibody, TNFA antibody, cTNF antibody, TNF receptor superfamily member 1A antibody, tumor necrosis factor receptor superfamily, member 1a antibody, TNF receptor superfamily member 1A S homeolog antibody, tumor necrosis factor antibody, TNFRSF1A antibody, Tnfrsf1a antibody, tnfrsf1a.S antibody, tnfrsf1a antibody, TNF antibody
Background
TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD. TNF Receptor I can also activate the transcription factor NFkB via TRAF2 (TNF Receptor associated factor 2). The cytoplasmic domain of TNF Receptor I can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade. TNF Receptor I is expressed by virtually all nucleated mammalian cells, including hepatocytes, monocytes and neutrophils, cardiac muscle cells, endothelial cells, and CD34 + hematopoietic progenitors. Both TNF alpha and TNF beta bind to TNF Receptor I.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Molecular Weight
50.5 kDa (NP_001056.1)
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , Hepatitis C , Ubiquitin Proteasome Pathway
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