RNF130
Reactivity: Human, Mouse, Rat
WB, IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 555
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Add 100 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Rnf130 antibody, G1RZFP antibody, GOLIATH antibody, GP antibody, 2510042A13Rik antibody, G1rp antibody, ring finger protein 130 antibody, Rnf130 antibody, RNF130 antibody
Background
RNF130 contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. RNF130 acts as an E3 ubiquitin-protein ligase and is ubiquitously expressed.Synonyms: E3 ubiquitin-protein ligase RNF130, Goliath homolog, H-Goliath, RING finger protein 130