Caspase 1 antibody (AA 1-100)

Catalog No. ABIN560170

This Mouse Monoclonal antibody specifically detects Caspase 1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for Caspase 1 antibody (AA 1-100) (ABIN560170)

Target: Caspase 1 (CASP1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3D2

Product Details anti-Caspase 1 Antibody

Binding Specificity: AA 1-100

Purpose: Mouse monoclonal antibody raised against a partial recombinant CASP1.

Sequence: MADKVLKEKR KLFIRSMGEA PQAVQDNPAM PTSSGSEGNV KLCSLEEAQR IWKQKSAEIY PIMDKSSRTR LALIICNEEF DSIPRRTGAE VDITGMTMLL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CASP1 (AAH62327, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Caspase 1 antibody (ABIN560170)

Choi, Stottmann, Yang, Meyers, Klingensmith: "The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis." in: Circulation research, Vol. 100, Issue 2, pp. 220-8, (2007) (PubMed).

Valenzuela, Economides, Rojas, Lamb, Nuñez, Jones, Lp, Espinosa, Brannan, Gilbert: "Identification of mammalian noggin and its expression in the adult nervous system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 15, Issue 9, pp. 6077-84, (1995) (PubMed).

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1

Background: Full Gene Name: caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Synonyms: ICE,IL1BC,P45

Gene ID: 834

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome