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Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody

Details for Product No. ABIN560397, Supplier: Log in to see
Antigen
  • AL118368
  • CIC-2
  • CLC-2
  • clC-2
  • ClC-2
  • Clc2
  • CLC2
  • CLCN2
  • ECA2
  • ECA3
  • EGI3
  • EGI11
  • EGMA
  • EJM6
  • EJM8
  • LOC100150892
  • nmf240
Epitope
AA 38-387, full length
17
16
13
9
5
3
2
1
1
Reactivity
Human
63
15
13
3
3
3
1
1
Host
Mouse
35
19
11
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
RNA Interference (RNAi), ELISA, Western Blotting (WB)
51
41
10
7
2
1
Supplier
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Immunogen CLCN2 (AAH21578.1, 38 a.a. ~ 387 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: TVSTAVIVFE LTGQIAHILP VMIVVILANA VAQSLQPSLY DSIIRIKKLP YLPELGWGRH QQYRVRVEDI MVRDVPHVAL SCTFRDLRLA LHRTKGRMLA LVESPESMIL LGSIERSQVV ALLGAQLSPA RRRQHMQERR ATQTSPLSDQ EGPPTPEASV CFQVNTEDSA FPAARGETHK PLKPALKRGP SVTRNLGESP TGSAESAGIA LRSLFCGSPP PEAASEKLES CEKRKLKRVR ISLASDADLE GEMSPEETHT IFSLLGVDHA YVTSIGRLIG IVTLKELRKA IEGSVTAQGV KVRPPLASFR DSATSSSDTE TTEVHALWGP HSRHGLPREG SPSDSDDKCQ
Clone 3E1
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name CLCN2 (CLCN2 Antibody Abstract)
Background Full Gene Name: chloride channel 2
Synonyms: CIC-2,CLC2,ECA3,EGI3,EGMA
Gene ID 1181
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) CLCN2 monoclonal antibody (M01), clone 3E1 Western Blot analysis of CLCN2 expression ...
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2...
Western Blotting (WB) image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 mono...
 image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Western Blot detection against Immunogen (64.24 KDa) .
ELISA image for anti-Chloride Channel 2 (CLCN2) (AA 38-387), (full length) antibody (ABIN560397) Detection limit for recombinant GST tagged CLCN2 is 0.3 ng/ml as a capture antibody.
Background publications Cantley, Neel: "New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4240-5, 1999 (PubMed).

Kandel, Hay: "The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB." in: Experimental cell research, Vol. 253, Issue 1, pp. 210-29, 1999 (PubMed).

Alessi, Andjelkovic, Caudwell, Cron, Morrice, Cohen, Hemmings: "Mechanism of activation of protein kinase B by insulin and IGF-1." in: The EMBO journal, Vol. 15, Issue 23, pp. 6541-51, 1997 (PubMed).

Product cited in: Datta, Dudek, Tao, Masters, Fu, Gotoh, Greenberg: "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery." in: Cell, Vol. 91, Issue 2, pp. 231-41, 1997 (PubMed).