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CLCN2 Products

(Chloride Channel 2 (CLCN2))

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This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].

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Featured CLCN2 Categories

CLCN2 Antibodies

High quality antibodies with extensive validation data.

CLCN2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CLCN2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (5)
Cat. No. ABIN560397
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7147577
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6260873
Quantity 100 μL
Datasheet Datasheet

Recommended CLCN2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349566
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349564
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137422
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CLCN2 products

Ferrer, Corneo, Davis, Wan, Miyagishima, King, Maminishkis, Marugan, Sharma, Shure, Temple, Miller, Bharti: "A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium." in: Stem cells translational medicine, Vol. 3, Issue 8, pp. 911-22, (2014) (PubMed).

Cornejo, Niemeyer, Zúñiga, Yusef, Sepúlveda, Cid: "Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval." in: Journal of cellular physiology, Vol. 221, Issue 3, pp. 650-7, (2009) (PubMed).

Haug, Warnstedt, Alekov, Sander, Ramírez, Poser, Maljevic, Hebeisen, Kubisch, Rebstock, Horvath, Hallmann, Dullinger, Rau, Haverkamp, Beyenburg, Schulz, Janz, Giese, Müller-Newen, Propping, Elger et al.: "Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. ..." in: Nature genetics, Vol. 33, Issue 4, pp. 527-32, (2003) (PubMed).

Sander, Schulz, Saar, Gennaro, Riggio, Bianchi, Zara, Luna, Bulteau, Kaminska, Ville, Cieuta, Picard, Prudhomme, Bate, Sundquist, Gardiner, Janssen, de Haan, Kasteleijn-Nolst-Trenité, Bader, Lindhout et al.: "Genome search for susceptibility loci of common idiopathic generalised epilepsies. ..." in: Human molecular genetics, Vol. 9, Issue 10, pp. 1465-72, (2000) (PubMed).

Datta, Dudek, Tao, Masters, Fu, Gotoh, Greenberg: "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery." in: Cell, Vol. 91, Issue 2, pp. 231-41, (1997) (PubMed).

Synonyms and alternative names related to CLCN2

chloride voltage-gated channel 2 (CLCN2), chloride channel, voltage-sensitive 2a (clcn2a), chloride channel protein 2 (EHI_142170), chloride channel protein 2 (EHI_186860), chloride channel, voltage-sensitive 2 (Clcn2), chloride voltage-gated channel 2 (Clcn2), AL118368, CIC-2, ClC-2, CLC-2, clC-2, CLC2, Clc2, CLCN2, ECA2, ECA3, EGI3, EGI11, EGMA, EJM6, EJM8, LOC100150892, nmf240

Protein level used designations for CLCN2

  • chloride channel 2
  • novel protein similar to vertebrate chloride channel 2 (CLCN2)
  • chloride channel protein 2
  • PKA-activated chloride channel ClC-2G
  • clC-2
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