FANCG antibody (AA 1-622)

Catalog No. ABIN560843

Product Details anti-FANCG Antibody

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Binding Specificity: AA 1-622

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FANCG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Purpose: Mouse monoclonal antibody raised against a full length recombinant FANCG.

Sequence: MSRQTTSVGS SCLDLWREKN DRLVRQAKVA QNSGLTLRRQ QLAQDALEGL RGLLHSLQGL PAAVPVLPLE LTVTCNFIIL RASLAQGFTE DQAQDIQRSL ERVLETQEQQ GPRLEQGLRE LWDSVLRASC LLPELLSALH RLVGLQAALW LSADRLGDLA LLLETLNGSQ SGASKDLLLL LKTWSPPAEE LDAPLTLQDA QGLKDVLLTA FAYRQGLQEL ITGNPDKALS SLHEAASGLC PRPVLVQVYT ALGSCHRKMG NPQRALLYLV AALKEGSAWG PPLLEASRLY QQLGDTTAEL ESLELLVEAL NVPCSSKAPQ FLIEVELLLP PPDLASPLHC GTQSQTKHIL ASRCLQTGRA GDAAEHYLDL LALLLDSSEP RFSPPPSPPG PCMPEVFLEA AVALIQAGRA QDALTLCEEL LSRTSSLLPK MSRLWEDARK GTKELPYCPL WVSATHLLQG QAWVQLGAQK VAISEFSRCL ELLFRATPEE KEQGAAFNCE QGCKSDAALQ QLRAAALISR GLEWVASGQD TKALQDFLLS VQMCPGNRDT YFHLLQTLKR LDRRDEATAL WWRLEAQTKG SHEDALWSLP LYLESYLSWI RPSDRDAFLE EFRTSLPKSC DL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: FANCG (AAH11623, 1 a.a. ~ 622 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2C8

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FANCG antibody (ABIN560843)

Kulkarni, Fortunato: "Stimulation of homology-directed repair at I-SceI-induced DNA breaks during the permissive life cycle of human cytomegalovirus." in: Journal of virology, Vol. 85, Issue 12, pp. 6049-54, (2011) (PubMed).

Tsai, Lin, Chiang, Lee, Lee, Ko: "Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 123, Issue 2, pp. 480-90, (2011) (PubMed).

Hinz, Nham, Yamada, Tebbs, Salazar, Hinz, Mohrenweiser, Jones, Thompson: "Four human FANCG polymorphic variants show normal biological function in hamster CHO cells." in: Mutation research, Vol. 602, Issue 1-2, pp. 34-42, (2006) (PubMed).

Target Details for FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Alternative Name: FANCG (FANCG Products)

Synonyms: xFANCG antibody, FAG antibody, XRCC9 antibody, AU041407 antibody, Xrcc9 antibody, Fanconi anemia complementation group G S homeolog antibody, Fanconi anemia complementation group G antibody, Fanconi anemia, complementation group G antibody, fancg.S antibody, FANCG antibody, Fancg antibody

Background: Full Gene Name: Fanconi anemia, complementation group G
Synonyms: FAG,XRCC9

Gene ID: 2189

Pathways: DNA Damage Repair