Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
50 % glycerol
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Ushioda, Hoseki, Nagata: "Glycosylation-independent ERAD pathway serves as a backup system under ER stress." in: Molecular biology of the cell, Vol. 24, Issue 20, pp. 3155-63, (2013) (PubMed).
Ushioda, Hoseki, Araki, Jansen, Thomas, Nagata: "ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER." in: Science (New York, N.Y.), Vol. 321, Issue 5888, pp. 569-72, (2008) (PubMed).
Corazzari, Lovat, Armstrong, Fimia, Hill, Birch-Machin, Redfern, Piacentini: "Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57." in: British journal of cancer, Vol. 96, Issue 7, pp. 1062-71, (2007) (PubMed).
Target
DNAJC10
(DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))